Table 1.
Numbers of differentially expressed genes in human monocytesa
| Gene type | No. of genes in monocytes incubated withb: |
||
|---|---|---|---|
| N. meningitidis | IL-10 | N. meningitidis plus IL-10 | |
| Differentially expressed | 3,579 | 648 (263) | 2,316 (1,799) |
| Upregulated | 872 | 297 (69) | 870 (555) [189] |
| Downregulated | 2,707 | 351 (194) | 1,446 (1,244) [163] |
| Eligible for Ingenuity Pathway Analysis | 2,994 | 541 | 1,951 |
a
Numbers of differentially expressed genes in human monocytes incubated with N. meningitidis, IL-10, and both for 3 h, analyzed versus unstimulated monocytes.
b
Criteria for cutoff: FC ≥ |1.5|, P < 0.01. Parentheses show the number of genes in the expression profile induced by incubating with N. meningitidis alone. Square brackets show the number of genes only expressed in the expression profile induced by incubating with both N. meningitidis and IL-10.