Table 3.
Effect of dCMP deaminase deficiency on spontaneous mutation ratea
| Strain | Mutation frequencyb (per 108/generation) | CI | Ratioc |
|---|---|---|---|
| Wild type | 3.9986 | 5.25–2.36 | 1.0 |
| rad2Δ | 41.1053 | 68.64–27.55 | 10.3 |
| dcd1Δ | 4.2736 | 6.11–3.22 | 1.1 |
| brc1Δ | 2.8495 | 3.78–1.74 | 0.7 |
| dcd1Δ brc1Δ | 15.1217 | 26.91–7.81 | 3.8 |
a
Mutation rates are the averages from three or more experiments. CI is the 95% confidence interval (10−8 per cell division).
b
Mutation rates were calculated by using the Lea-Coulson method of the median (20).
c
Ratio is relative to the wild type.