Fig. 1.

Effects of suramin and kynurenate microinjections into the NTS on mean arterial pressure (MAP). a Representative time-line of an experimental protocol involving blockade of both P2 and glutamate receptors in the NTS and stimulation of the HDA. b Bilateral microinjections of suramin (10 mM) or kynurenate (50 mM) into the NTS elicited a transitory increase in MAP baseline (N = 5). The values of MAP returned to in resting condition after ∼30 min, for suramin, and kynurenate. No further increase in MAP was elicited by kynurenate, after previous blockade with suramin