Table 1.
Suramin + kynurenate NTS | Kynurenate NTS | Suramin + kynurenate RVLM | ||||||
---|---|---|---|---|---|---|---|---|
Control | Sur NTS | Sur + kyn NTS | Control | Kyn NTS | Control | Sur RVLM | Sur + kyn RVLM | |
MAP (mmHg) | 110 ± 4 | 109 ± 8 | 105 ± 8 | 100 ± 10 | 108 ± 6 | 115 ± 1 | 122 ± 7 | 114 ± 5 |
HR (bpm) | 362 ± 15 | 329 ± 16 | 301 ± 27 | 347 ± 18 | 369 ± 21 | 364 ± 13 | 359 ± 16 | 299 ± 5 * |
HVC (μl/mmHg*min) | 100 ± 11 | 112 ± 16 | 91 ± 11 | 96 ± 8 | 102 ± 15 | 85 ± 13 | 64 ± 7 | 68 ± 11 |
*P < 0.05 in comparison to control level