Table 1.
Demographic and clinical characteristics of Buruli ulcer cases diagnosed in travelers to Queensland and the Northern Territory, Australia
| Case no. | Age (yrs) | Sex | Residential addressa | Site and form of disease | Diagnosisb | Treatment | Onset of symptoms | Travel history/possible exposuresa | Origin of infectiona | Incubation period |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 69 | Male | VIC | Left leg ulcer | PCR, culture | Surgery and antibiotics (RIF + MXF) | December 2009 (boil) | VIC (Barwon Heads), July 2009 (<1 h); NT (Darwin, Kakadu, Daly River), July 2009 (10 days) | NT | 5 months |
| 2 | 32 | Male | VIC | Left calf ulcer | PCR, culture, histology | Antibiotics (RIF + CLR) | January 2011 (nontender papule) | QLD (Daintree), October 2010 (5 days); VIC (Point Lonsdale), January 2011 (1 day) | QLD | 3 months |
| 3 | 65 | Female | NSW | Left leg ulcer | PCR, culture, histology | Antibiotics (RIF + CIP) | December 2010 (painless papule) | QLD (Daintree, Mossman), October 2010 (3 weeks) | QLD | 2 months |
| 4 | 64 | Female | WA | Left thigh nonulcerated lesion | PCR | Surgery and antibiotics (RIF + CLR) | April 2011 (itchy lesion) | VIC (Drysdale), January 2011(2 weeks); QLD (Daintree), January 2011 (7 days) | QLD | 3 months |
| 5 | 60 | Female | SA | Right ankle ulcer | PCR, culture | Surgery and antibiotics (RIF + MXF) | June 2011 | South Africa, Mozambique, Zimbabwe, Kenya, and Uganda, 2001–2009 (8 yrs); QLD (Mossman, Port Douglas, Miallo), January 2011 (2–3 weeks) | QLD | 5 months |
a
NSW, New South Wales; NT, Northern Territory; QLD, Queensland; SA, South Australia; VIC, Victoria; WA, Western Australia.
b
All cases were confirmed by PCR targeting the M. ulcerans-specific insertion element IS2404. No fresh tissue was available for culture from case 4.