Fig 6.
Inhibition of CpG-induced IFN-α production by HA. Freshly isolated pDCs were treated with sH53N7, produced in HEK293T, KIF-treated HEK293T, HEK293S GnTI(−), and S2 cells, in the presence of CpG. The culture supernatants were collected after 18 h for IFN-α quantification by ELISA. The data shown are from one representative experiment out of four independent experiments with pDCs from four different donors. Significant differences between groups treated with the different HA protein preparations are indicated: ***, P < 0.001.