Table 2.
Selected genes upregulated 2-fold or more under hyperosmotic stress
| Functional class and protein | Gene | Locus tag | Fold upregulation at: |
||||
|---|---|---|---|---|---|---|---|
| 15 min | 1.5 h | 3 h | 6 h | 12 h | |||
| Regulation and signal transduction | |||||||
| Campylobacter bile response regulator | cbrR | cj0643 | 2.2 | 2.9 | 2.9 | ||
| Heat-inducible transcription repressor | hrcA | cj0757 | 6.7 | 2.0 | 2.2 | 2.6 | 2.9 |
| Bipartate energy taxis response protein | cetB | cj1189c | 2.2 | 3.5 | 3.3 | 2.1 | |
| Bipartate energy taxis response protein | cetA | cj1190c | 2.0 | 3.6 | 2.4 | 2.1 | |
| Heat shock transcriptional regulator | hspR | cj1230 | 3.1 | ||||
| Putative helix-turn-helix-containing protein | cj1533c | 3.5 | 2.8 | 2.6 | 2.3 | 2.0 | |
| Detoxification and protection | |||||||
| Superoxide dismutase | sodB | cj0169 | 2.0 | 2.5 | 2.4 | ||
| Catalase | katA | cj1385 | 2.2 | 2.2 | |||
| Chaperones, chaperonins, heat shock, proteases | |||||||
| ATP-dependent Clp protease | clpB | cj0509c | 2.3 | ||||
| Heat shock protein | grpE | cj0758 | 9.4 | 2.2 | 2.5 | 2.6 | 4.0 |
| Heat shock protein | dnaK | cj0759 | 12.8 | 2.4 | 2.8 | 2.5 | 6.9 |
| 60-kDa chaperonin | groEL | cj1221 | 6.9 | 3.0 | 5.0 | 2.6 | |
| Putative curved-DNA binding protein | cbpA | cj1229 | 2.7 | ||||
| Amino acid biosynthesis | |||||||
| Glutamate synthase | gltD | cj0009 | 4.8 | ||||
| Putative anthranilate synthase component I | trpE | cj0345 | 2.1 | 3.1 | 13.9 | ||
| N-(5′-Phosphoribosyl)anthranilate isomerase | trpF | cj0347 | 3.4 | 2.9 | 4.4 | 2.9 | 3.5 |
| Tryptophan synthase beta chain | trpB | cj0348 | 3.0 | 3.2 | 5.1 | 3.0 | |
| Tryptophan synthase alpha chain | trpA | cj0349 | 3.1 | 3.1 | 4.6 | 2.0 | 3.1 |
| Glutamine synthetase | glnA | cj0699c | 5.3 | ||||
| Cysteine synthase | cysM | cj0912c | 2.2 | 3.8 | 3.8 | 2.4 | |
| Putative cystathionine beta-lyase | cj1392 | 2.4 | 4.1 | 3.8 | 2.9 | 3.9 | |
| 3-Isopropylmalate dehydratase small subunit | leuD | cj1716c | 2.7 | 4.3 | 3.1 | ||
| 3-Isopropylmalate dehydratase large subunit | leuC | cj1717c | 2.4 | 3.4 | 6.5 | 3.4 | |
| 3-Isopropylmalate dehydrogenase | leuB | cj1718c | 2.4 | 3.8 | 7.3 | 3.5 | |
| 2-Isopropylmalate synthase | leuA | cj1719c | 2.2 | 3.1 | 6.1 | 3.3 | |
| ATP synthesis | |||||||
| ATP synthase Fo sector, subunit B′ | atpF′ | cj0102 | 3.5 | ||||
| ATP synthase Fo sector subunit B | atpF | cj0103 | 4.9 | ||||
| ATP synthase F1 sector delta subunit | atpH | cj0104 | 2.1 | 4.3 | |||
| ATP synthase F1 sector alpha subunit | atpA | cj0105 | 2.2 | 3.7 | |||
| ATP synthase F1 sector gamma subunit | atpG | cj0106 | 2.1 | 3.6 | |||
| ATP synthase F1 sector beta subunit | atpD | cj0107 | 3.4 | ||||
| ATP synthase Fo sector C subunit | atpC | cj0936 | 2.3 | 2.6 | |||
| Transport/binding proteins | |||||||
| Putative MATE family transport protein | cj0560 | 2.2 | 2.0 | 2.1 | |||
| Degenerate K+-transporting ATPase, B subunit | kdpB | cj0677 | 2.1 | ||||
| Aspartate/glutamate binding ABC transporter | peb1B | cj0921c | 2.2 | ||||
| Putative glutamine permease | glnP | cj0940c | 2.4 | ||||
| Surface, polysaccharides, antigens | |||||||
| Putative periplasmic protein | cj0561c | 5.4 | 5.0 | 11.2 | 9.2 | 11.8 | |
| Major antigenic peptide PEB2 | peb2 | cj0778 | 2.1 | 3.0 | 2.9 | 2.1 | |
| 50-kDa outer membrane protein precursor | omp50 | cj1170c | 4.3 | ||||
| Capsule polysaccharide export system | kpsM | cj1448c | 2.1 | 2.0 | 2.5 | 3.2 | |
| Miscellaneous | |||||||
| Protease | pspA | cj0068 | 2.2 | 2.0 | 3.7 | ||
| Peptidyl-tRNA hydrolase | pth | cj0312 | 2.2 | 2.9 | 3.1 | 3.6 | 3.8 |
| Putative endoribonuclease L-PSP | cj1388 | 2.2 | 2.9 | 3.0 | 3.2 | 2.7 | |