Table 2.

All the genes shared by 57 (Alpha-, Beta-, and Gammabaculovirus), 55 (Alpha-, Beta-, and Deltabaculovirus), and 54 (Alpha- and Betabaculovirus) members^a

AcMNPV ORF	Gene designation	Description	CpGV ORF	NeabNPV ORF	Previously reported genus(era)	Genera determined in this work	Method of Detection
Core genes for the genera Alpha-, Beta-, and Gammabaculovirus
8	polyhedrin granulin	OB protein	1	1	α + β + γ	α + β + γ	Multi PSI-Blast/HaMStR
25	dbp	DNA binding protein	81	6	α + β + γ	α + β + γ	Multi PSI-Blast/HaMStR
37	lef-11	Required for expression of late genes	58	7	α + β + γ	α + β + γ	Multi PSI-Blast/HaMStR
61	fp/25k	Structural protein of BVs and ODVs	118	54	α + β	α + β + γ	Multi PSI-Blast
75	ac75	Required for BV production	108	43	α + β	α + β + γ	Multi PSI-Blast/HaMStR
106/107	ac106/107	Unknown function	52	35	α + β	α + β + γ	Multi PSI-Blast/HaMStR
108	ac108	P11 protein, associated with the PIF complex	56	72	α + β	α + β + γ	Multi PSI-Blast/HaMStR
131	pe/pp34	Involved in morphogenesis of polyhedral envelope	23	53	α	α + β + γ	Multi PSI-Blast
145	ac145	OB protein, involved in oral infection	9	67	α + β	α + β + γ	Multi PSI-Blast/HaMStR
Core gene for the genera Alpha-, Beta-, and Deltabaculovirus
23	ac23	Pathogenicity factor in alphabaculoviruses of group I; fusion protein in alphabaculoviruses of group II, betabaculoviruses, and gammabaculoviruses	31	104b	α + β + δ	α + β + δ	Multi PSI-Blast/HaMStR
Core genes for the genera Alpha- and Betabaculovirus
10	pk-1	Protein kinase	3		α + β	α + β	Multi PSI-Blast
13	ac13	Unknown function	73		α + β	α + β	Multi PSI-Blast
28	lef-6	Involved in late and very late gene expression	80		α + β	α + β	Multi PSI-Blast
35	ubiquitin	Ubiquitin	54		α + β	α + β	Multi PSI-Blast
36	pp31	Late gene expression factor	57		α + β	α + β	Multi PSI-Blast
38	ac 38	ADP-ribose pyrophosphatase	69		α + β	α + β	Multi PSI-Blast
64	gp37	Chitin binding protein/spindle body protein	13		α	α + β	Multi PSI-Blast
67	lef-3	ssDNA binding protein	113		α + β	α + β	Multi PSI-Blast
82	tlp	Unknown function	102		α + β	α + β	Multi PSI-Blast
102	p12	Involved in nuclear localization of G-actin	84		α + β	α + β	Multi PSI-Blast/HaMStR
110	ac110	Unknown function	53		α	α + β	Multi PSI-Blast
129	p24	ODV protein	71		α	α + β	Multi PSI-Blast
139	me53	DNA synthesis regulator, required for efficient BV production	143		α	α + β	Multi PSI-Blast
141	Exon0	Egress of nucleocapsids from the nucleus to the cytoplasm, interaction with β-tubulin and microtubules	11		α	α + β	Multi PSI-Blast
146	ac146	Unknown function	8		α + β	α + β	Multi PSI-Blast
147	ie-1	Immediate-early transactivator	7		α + β	α + β	Multi PSI-Blast

^aBoldface type represents new core genes proposed by this work. The Greek letters α, β, γ, and δ are used to indicate the genera Alpha-, Beta-, Gamma-, and Deltabaculovirus, respectively. ssDNA, single-stranded DNA.

^bCuniNPV ORF.