. 2012 Nov;86(22):12105–12114. doi: 10.1128/JVI.01352-12

Table 5.

Mutational analysis to locate amino acid residues responsible for differences in sensitivity/resistance to neutralization by HIV-positive sera possessing broadly neutralizing antibodies^a

Subject or virus	Clone	Phenotype or mutation	Neutralization titer (IC₅₀) of HIV-positive serum (1/dilution)
Subject or virus	Clone	Phenotype or mutation	Z23	N16	Z1679
172297	013	wtR	230	40	133
	028	wtS	12,161	1,839	4,124
	013	Y384H/L702P	10,285	1,304	2,736
	013	T60A/N136K	267	<100	153
	013	Y384H	3,219	480	793
	013	L702P	2,089	428	787
	013	D460N/S465N	298	<100	<100
	013	L345I	417	51	208
	013	V535A	519	<100	241
172946	008	wtR	198	52	167
	025	wtS	6,245	1,557	2,671
	008	I423T/G589D	6,434	1,202	2,224
	008	I423T	1,275	200	561
	008	G589D	128	<100	119
	008	K92E/S142G	258	43	172
	008	R696K/F765L	184	<100	133
JRCSF			337	196	164
NL4-3			3,708	1,543	3,701
aMLV			<100	<100	<100

Refer to the footnote to Table 3 for details.