. Author manuscript; available in PMC: 2013 Feb 1.

Published in final edited form as: Food Chem Toxicol. 2011 Nov 3;50(2):341–352. doi: 10.1016/j.fct.2011.10.065

Table IV.

Genes downregulated by dietary exposure to DBC compared to chemo-intervention

		Mean fold change in gene expression^a
Gene	Annotation (DFCI accession / GenBank accession)	DBC ^b	DBC+Chl ^c	Chl ^d
Growth factor
FGF6	NP544420 / Y16850	−1.00	-	-
Immune response
IGF1	NP544251 / M95183	−1.25	-	-
LECT2	TC154068 / AF363272		−1.15	-
Metabolism
Vtg1	TC132491 / X92804	−1.20	-	-
Extracellular matrix
MMP	TC147381 / AB043536	−1.26	-	-

Mean fold changes in gene expression were log₂ transformed. Only probes that differed by an average of at least twofold between treatment and control groups and were significant (P<0.05) are reported.

224 ppm DBC was administered via the diet for 20 days and liver samples for RNA were collected at the end of the 20 day exposure period.

224 ppm DBC + 2000ppm Chl were co-administered via the diet for 20 days and liver samples for RNA were collected at the end of the 20 day exposure period.

2000 ppm Chl were co-administered via the diet for 20 days and liver samples for RNA were collected at the end of the 20 day exposure period.