Graphic model illustrating the inhibitory action (T-shaped lines) of the antibiotics (BAC, bacitracin; DAP, daptomycin; MER, mersacidin; NIS, nisin; VAN, vancomycin) used in this study and the mechanism of stimulus perception (flash-shaped arrows) resulting in activation of the biosensors PbceA and PliaI (stars) in both rod-shaped cells (A) and L-forms (B). CM, cytoplasmic membrane; CW, cell wall. The lipid II cycle and incorporation of cell wall building blocks are indicated by the two black bent arrows. Activation of the LiaRS (Lia) or BceRS (Bce) TCS is indicated by white letters on a black background, while an inactive system is indicated by black letters on a white background. See the text for details.