Fig 2.

Effect of the fragments of LL-37 on the permeability to PI. A PAO1 bacterial suspension was incubated at 37°C for 1 h in the presence of 10 μM PI and various concentrations of N-terminal fragments (A), intermediate fragments (B), or C-terminal fragments (C). For comparison, LL-31 and LL-25 were also plotted in panel B. The results are the variations of the fluorescence provoked by the peptides and are expressed as arbitrary units (a.u.). They are the means ± SEM of two to four independent experiments performed in duplicate.