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Probabilities of target attainment for the four population PK models (Table 2) and different dosage regimens of piperacillin (PK/PD target, fT>MIC of ≥50%). ▲, first-order renal and first-order nonrenal elimination (model 1); □, mixed-order renal and first-order nonrenal elimination (model 2); ◊, parallel first- and mixed-order renal and first-order nonrenal elimination (model 3); and ○, parallel first- and mixed-order renal and mixed-order nonrenal elimination (model 4).
