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Detailed plasma concentration-time curve plots for 7 subjects classified as late responders (LR) and 5 subjects classified as late treatment failures (LTF). Notably, no LR subjects went on to become LTF. Subject identification (ID) numbers are followed by artesunate dosing groups (AS2, AS4, and AS6 for artesunate doses of 2, 4, and 6 mg/kg, respectively). The lower limit of quantitation (LLOQ) by LC-MS for DHA is shown as a dotted line.
