Table 1.

Effects of the eight compounds described in this study^a

Name	Compound identifier	Effect	% I/E	EC50 (μM)	Likely target	Compound effect on growth	Motility	Invasion
C1	F1115-0016	INH	0.17 ± 0.1	1.36 ± 3.54	Parasite	IRR	INH	INH
C2	F1041-0001	INH	0.19 ± 0.1	1.34 ± 0.27	Parasite	IRR	NE	NE
C3	F3215-0002	INH	0.65 ± 0.1	0.57 ± 0.06	Parasite	REV	ENH	NE
C5	F0909-0123	INH	1.82 ± 2.2	1.12 ± 0.18	Parasite	IRR	INH	NE
C8	F0406-1005	ENH	205.3 ± 7.6	0.14 ± 0.02	Host cell	IRR	NE	NE
C11	F0745-0014	ENH	213.8 ± 18.8	0.21 ± 0.05	Host cell	IRR	NE	NE
C12	F0862-0340	ENH	214.1 ± 31.0	1.19 ± 0.22	Unknown	REV	ENH	NE
C13	F3220-0514	ENH	220.3 ± 1.3	0.38 ± 0.26	Unknown	REV	NE	NE

^aAbbreviations: % I/E, percent inhibition or enhancement compared to vehicle control at 10 μM; IRR, irreversible; REV, reversible; INH, inhibitor; ENH, enhancer; NE, no effect.