Table 3.

Multivariate logistic regression models of the relationship between serum FGF23 and cardiovascular disease in 659 women, aged 70–79 years, in the Women’s Health and Aging Studies, for all participants and stratified by chronic kidney disease at baseline¹

		Model 1			Model 2			Model 3
		Adjusted for age, race, smoking, education, body mass index, MMSE, diabetes, and hypertension			Adjusted for age, race, smoking, education, body mass index, MMSE, diabetes, hypertension, and physical activity			Adjusted for age, race, smoking, education, body mass index, cognition, diabetes, hypertension, physical activity, total cholesterol, HDL cholesterol, and renal function
		O.R.	95 % CI	P	O.R.	95 % CI	P	O.R.	95 % CI	P
All participants		1.26	1.20, 1.33	<0.0001	1.23	1.16, 1.30	<0.0001	1.24	1.18, 1.31	<0.0001
Chronic kidney disease2	Absent	1.14	1.05, 1.24	0.001	1.10	1.01, 1.19	0.04	1.10	1.01, 1.20	0.03
	Present	1.41	1.30, 1.53	<0.0001	1.42	1.31, 1.55	<0.0001	1.44	1.32, 1.57	<0.0001

¹Odds Ratio (OR) expressed per 1 SD of log serum FGF23 (1 SD = 0.52 pg/mL).

²For analyses stratified by chronic kidney disease, model 3 includes all covariates above except renal function.