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Gaining Optimal Asthma Control (GOAL) study: Mean rate of exacerbations requiring either oral steroids or hospitalization/emergency visits per patient per year over the one-year study period according to inhaled corticosteroid (ICS) use in the previous six months. P≤0.009 salmeterol/fluticasone versus fluticasone alone, all strata. Reproduced with permission from reference 64. © 2004 American Thoracic Society
