Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
ACAT inhibitory activity and increase of ABCA1 gene expression of the most active TP compounds and CI-976 in MC65 cells.
| Compound | IC50 value of ACAT inhibition (μM) | EC50 value of ABCA1 gene expression (μM) |
|---|---|---|
| 1 | 1.2 ± 0.2 | 0.9 ± 0.1 |
| 2b | 0.3 ± 0.08 | 1.1 ± 0.1 |
| 2e | 1.4 ± 0.2 | 2.5 ± 0.4 |
| 3f | 1.8 ± 0.3 | 2.2 ± 0.2 |
| 4a | 0.8 ± 0.06 | 1.3 ± 0.1 |
| CI-976 | 0.2 ± 0.1 | 0.6 ± 0.07 |
