Table 2.

Molecular Biology core classes with their definitions are listed

LS DAM class	Definition
AminoAcidPhysicalLocation	A physical location within an amino acid sequence
AminoAcidSequence	A representation of the linear arrangement of the molecules known as amino acid residues
Chromosome	A structure composed of a very long molecule of DNA and associated proteins (eg, histones) that carries hereditary information
DNASequence	A representation of the linear arrangement of deoxyribonucleotides comprising a DNA polymer
Exon	A portion of a gene sequence that is transcribed into the final mRNA product
Gene	A functional unit of heredity which occupies a specific position (locus) on a particular chromosome, is capable of reproducing itself exactly at each cell division, and directs the formation of a protein or other product
GeneticVariation	Deviation(s) in the nucleotide sequence of the genetic material of an individual from that typical of the group to which the individual belongs or deviation(s) in the nucleotide sequence of the genetic material of offspring from that of its parents
Genome	An assembly of the DNA sequence for the entire genome for a given organism
Intron	A portion of a gene sequence that is transcribed but excised from the mature mRNA during processing
MessengerRNA	A representation of (eg, as in public resources such as NCBI RefSeq or EBI Ensembl) a member of the class of RNA molecules that contains protein-coding information in its nucleotide sequence that can be translated into the amino acid sequence of a protein
NucleicAcidPhysicalLocation	A physical location within a nucleic acid sequence
Protein	A representation of (eg, as in public resources such as UniProt or NCBI RefSeq) an organic macromolecule composed of one or more chains (linear polymers) of α-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons
RNASequence	A representation of the linear arrangement of ribonucleotides comprising an RNA polymer

LS DAM, Life Sciences Domain Analysis Model.