Table 1. Comparison of the glycoside hydrolase (GH) profiles targeting plant structural polysaccharides in the snail, termite, giant panda, wallaby, and human metagenomes.
| CAZy Family | Known activity | SNAIL | TERMITE | WALLABY | PANDA | HUMAN |
| Cellulases | ||||||
| GH5 | cellulase | 36 | 125 | 27 | 1 | 7 |
| GH6 | endoglucanase | 4 | 0 | 0 | 0 | 0 |
| GH7 | endoglucanase | 0 | 0 | 0 | 0 | 0 |
| GH9 | endoglucanase | 15 | 43 | 5 | 0 | 0 |
| GH44 | endoglucanase | 0 | 0 | 0 | 0 | 0 |
| GH45 | endoglucanase | 0 | 6 | 0 | 0 | 0 |
| GH48 | endo-processive cellulases | 2 | 0 | 0 | 0 | 0 |
| Total | 57 (2) | 174 (16) | 32 (4) | 1 (0.5) | 7 (1) | |
| Endohemicellulases | ||||||
| GH8 | endo-xylanases | 46 | 21 | 2 | 1 | 2 |
| GH10 | endo-1,4-β-xylanase | 25 | 102 | 19 | 1 | 2 |
| GH11 | xylanase | 1 | 19 | 0 | 0 | 0 |
| GH12 | endoglucanase & xyloglucan hydrolysis | 0 | 0 | 0 | 0 | 0 |
| GH26 | β-mannanase & xylanase | 11 | 20 | 8 | 0 | 1 |
| GH28 | galacturonases | 69 | 15 | 10 | 0 | 3 |
| GH53 | endo-1,4-β-galactanase | 9 | 20 | 11 | 4 | 11 |
| Total | 161 (6) | 197 (18) | 50 (6) | 6 (2.5) | 19 (3) | |
| Cell wall elongation | ||||||
| GH16 | xyloglucanases & xyloglycosyltransferases | 12 | 6 | 6 | 6 | 1 |
| GH17 | 1,3-β-glucosidases | 2 | 0 | 0 | 0 | 0 |
| GH81 | 1,3-β-glucanase | 1 | 0 | 0 | 0 | 0 |
| Total | 15 (1) | 6 (1) | 6 (1) | 6 (3) | 1 (0) | |
| Debranching enzymes | ||||||
| GH51 | α-L-arabinofuranosidase | 22 | 13 | 19 | 2 | 15 |
| GH62 | α-L-arabinofuranosidase | 2 | 0 | 0 | 0 | 0 |
| GH67 | α-glucuronidase | 5 | 6 | 1 | 2 | 1 |
| GH78 | α-L-rhmnosidase | 73 | 7 | 46 | 1 | 13 |
| Total | 102 (4) | 26 (2) | 66 (8) | 5 (2) | 29 (5) | |
| Oligosaccharide-degrading enzymes | ||||||
| GH1 | β-glucosidase & many other β-linked dimers | 294 | 27 | 94 | 41 | 54 |
| GH2 | β-galactosidases & other β-linked dimer | 66 | 32 | 39 | 4 | 29 |
| GH3 | mainly β-glucosidases | 219 | 109 | 101 | 11 | 55 |
| GH29 | α-L-fucosidase | 70 | 12 | 5 | 0 | 7 |
| GH35 | β-galactosidase | 32 | 7 | 8 | 1 | 4 |
| GH38 | α-mannosidase | 18 | 18 | 3 | 8 | 6 |
| GH39 | β-xylosidase | 6 | 13 | 3 | 8 | 2 |
| GH42 | β-galactosidase | 54 | 33 | 17 | 7 | 15 |
| GH43 | arabinases & xylosidases | 185 | 63 | 72 | 13 | 34 |
| GH52 | β-xylosidase | 0 | 3 | 0 | 0 | 0 |
| Total | 944 (36) | 317 (28) | 342 (39) | 93 (41) | 206 (36) | |
Data are presented with the GHs grouped according to their major function roles in the degradation of plant fiber, as classified in Allgaier et al., 2010 [70]. The numbers in parentheses represent the percentages of these groups relative to the total number of GHs identified in the metagenomic datasets [2590 for snail, 872 for wallaby, 1117 for termite, 227 for panda (from 3 samples), and for human (from 2 samples)].