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. 2012 Nov 1;7(11):e47821. doi: 10.1371/journal.pone.0047821

Table 1. Patient details: clinical and demographic data.

Neglect*** (n = 55) No neglect (n = 105)
Sub-acute Chronic Sub-acute Chronic
Age in years (mean/SD) 69.3/12.3 N/A 68.3/12.7 N/A
Sex (M/F) 29/26 N/A 63/42 N/A
Aetiology (ISCH/BL) 47/8 N/A 97/8 N/A
Lesion size (mean/SD)* 62.0/87.4 cm3 N/A 40.6/65.6 cm3 N/A
Handedness (R/L) 49/6 N/A 92/13 N/A
Scan time since stroke days (mean/SD) 5.5/12.9 N/A 3.2/7.7 N/A
BUCS** in days (mean/SD) 28.5/21.5 280.3/14.1 21.3/17.3 282.1/16.3
Orient1 mean/SD (max/range) 7.5/1.3 (8/1–8) 7.8/0.6 (8/7–8) 7.6/1.2 (8/3–8) 7.8/0.9 (8/5–8)
Orient2 mean/SD (max/range) 5.4/1.0 (6/2–6) 5.6/0.9 (6/1–6) 5.7/0.7 (6/3–6) 5.9/0.3 (6/4–6)
Nosognosia (Orient3) mean/SD (max/range) 2.8/0.5 (3/0–3) 3.0/0.2 (3/2–3) 2.9/0.3 (3/1–3) 3.0/0.2 (3/2–3)
Left VE (uni asymmetry) mean/SD (max/range) 0.5/1.2 (4/0–4) 0.2/0.8(4/0–4) 0.1/0.4 (4/0–4) 0/0 (4/0)
Right VE (uni asymmetry) mean/SD (max/range) 0.4/1.1 (4/0–4) 0.3/1.0/(4/0–4) 0.1/0.7 (4/0–4) 0.1/0.7 (4/0–4)
Left VE (bilat asymmetry) mean/SD (max/range) 2.0/3.0 (8/0–8) 1.1/2.3 (8/0–8) 0.1/0.8 (8/0–8) 0.1/0.2 (8/0–1)
Right VE (bilat asymmetry) mean/SD (max/range) 0.7/2.2 (8/0–8) 0.6/2.1 (8/0–8) 0.3/1.4 (8/0–8) 0.2/1.0 (8/0–8)
ACT accuracy mean/SD (max/range) 28.4/14.7 (50/1–49) 38.2/11.1 (50/15–49) 47.4/4.4 (50/35–50) 46.9/4.0 (50/31–50)
ACT/AFA (left deficits) mean/SD (max/range) 4.8/6.0 (25/0–20) 2.8/4.4 (25/0–20) 0.4/0.7 (25/0–3) 0.5/1.0 (25/0–4)
ACT/AFA (right deficits) mean/SD (max/range) 1.0/2.2 (25/0–10) 1.3/3.2(25/0–14) 0.4/0.8 (25/0–4) 0.4/0.8 (25/0–2)
ACT/AIncA (left deficits) mean/SD (max/range) 3.1/5.1 (50/0–19) 1.3/3.0 (50/0–17) 0.1/0.2 (50/0–1) 0.1/0.4 (50/0–2)
ACT/AIncA (right deficits)mean/SD (max/range) 1.0/2.0 (50/0–11) 0.5/1.8 (50/0–6) 0.1/0.3 (50/0–1) 0.2/0.6(50/0–3)
*

Overall lesion size (volume) in the neglect group was not significantly larger than in the group without neglect symptoms (t(158) = 1.7, p>0.5);

**

For the acute/subacute phase the number of days indicate stroke to test (initial BUCS) interval and at the chronic phase number of days indicate the interval between initial BUCS test and follow up BUCS;

***

Patient who at sub-acute phase following stroke showed any type of neglect symptoms including egocentric and allocentric neglect for either left or right side of space; ACT, Apple Cancellation task; the maximum achievable score in the Apple Cancellation task is 50 (ACT accuracy). The cut-off for total numbers of target (full apples) omissions i.e. accuracy score is 40/50. Egocentric neglect is determined by whether patients miss targets (complete apples) on the left or right side of the page (asymmetry score calculated based on left- vs. right-side errors, ACT/AFA asymmetry score for full apples indicating either left or right deficits). Allocentric neglect is determined by whether patients make false positive responses by cancelling incomplete apples (distractors) where the gap is on either the right or left side of each apple, irrespective of the position of the (incomplete) apple on the page (asymmetry score calculated based on left- vs. right-side errors, AIncA asymmetry score for incomplete apples); BL, bleed/hemorrhagic stroke; F, female; ISCH, ischemic stroke L, left; M, male; max/range, maximum achievable score and range of scores within the group of patients; Orient1, orientation measure assessing personal information; Orient2, orientation measure assessing time and space awareness; R, right; SD; standard deviation; VE, visual extinction test, the task consists of 4 unilateral left, 4 unilateral right and 8 bilateral trials, asymmetry score calculated based on left- vs. right-side misses.