Table 2. Distance to the Nearest Exon of Intronic SNPs Tends to Be Smaller Than the Distance to the Skipped Exon of ISE SNPs.

Tested Exons and SNPs Category	Mean (bp)	Median (bp)	SD (bp)
dbSNP129
Distance to the nearest exon of intronic SNPs in dbSNP129	15655	4103	33620
Distance to the nearest exon of ISE SNPs in dbSNP129	13520	3934	28815
Distance to the skipped exon of ISE SNPs in dbSNP129	44212	13785	94435
Human Trait-SNPs (NHGRI GWAS)
Distance to the nearest exon of intronic SNPs in Human Trait-SNPs	12505	3095	26718
Distance to the nearest exon of ISE SNPs in Human Trait-SNPs	10177	3022	17863
Distance to the skipped exon of ISE SNPs in Human Trait-SNPs	14859	7111	18325

The upper 3 rows show the general distribution of the distance to the nearest exon of all intronic SNPs and the distance to the skipped exon of the ISE SNPs (Figure S3). The bottom 3 rows show the distribution of the distance to the nearest exon of trait-associated intronic SNPs and distance to the nearest exon of trait-associated ISE SNPs (Figure 7).