Table 2. Distance to the Nearest Exon of Intronic SNPs Tends to Be Smaller Than the Distance to the Skipped Exon of ISE SNPs.
Tested Exons and SNPs Category | Mean (bp) | Median (bp) | SD (bp) |
dbSNP129 | |||
Distance to the nearest exon of intronic SNPs in dbSNP129 | 15655 | 4103 | 33620 |
Distance to the nearest exon of ISE SNPs in dbSNP129 | 13520 | 3934 | 28815 |
Distance to the skipped exon of ISE SNPs in dbSNP129 | 44212 | 13785 | 94435 |
Human Trait-SNPs (NHGRI GWAS) | |||
Distance to the nearest exon of intronic SNPs in Human Trait-SNPs | 12505 | 3095 | 26718 |
Distance to the nearest exon of ISE SNPs in Human Trait-SNPs | 10177 | 3022 | 17863 |
Distance to the skipped exon of ISE SNPs in Human Trait-SNPs | 14859 | 7111 | 18325 |
The upper 3 rows show the general distribution of the distance to the nearest exon of all intronic SNPs and the distance to the skipped exon of the ISE SNPs (Figure S3). The bottom 3 rows show the distribution of the distance to the nearest exon of trait-associated intronic SNPs and distance to the nearest exon of trait-associated ISE SNPs (Figure 7).