Figure 4.

Constitutive active FOXO1 up-regulates human Sell core promoter activity in a dose-dependent manner.

Notes: Jurkat cells were transiently co-transfected with the combination of plasmids as labeled in the figure. Luciferase activity normalized to that of Renilla activity was analyzed 30 hours after transfection. Data were presented as mean ± SD of at least three independent experiments in triplicate on each transfection. Data were graphed as fold increase relative to that of pcDNA3 transfected Jurkat cells, which was set as 1.