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. 2012 Oct 25;8(10):e1002996. doi: 10.1371/journal.ppat.1002996

Figure 4. Loss of ACSL and ACAD function inhibits egg production.

Figure 4

A. Average basal OCR of fecund females incubated without (Ctrl) or with Triascin C (TC) over the first 30 min ex vivo. B. Numbers of eggs produced in 24 h per female parasite in the absence or presence of Triascin C. Average basal OCR (C & F), numbers of eggs produced in 72 h per female (D & G) and quantitation of Oil-Red-O staining (E) and measurement of FAO activity (H) in control fecund females, and in fecund females electroporated with SmASCL-siRNA (siASCL) or SmACAD-siRNA (siACAD), or with control siRNA (-ve siRNA). Data are means plus SEM of readings from 5–6 individual female worms per experiment. Data are representative of at least 2 individual experiments. See also Fig. S2.