A, voltage clamp recording obtained in an acute NTS slice from a neuron that responds to both pH 7.0 and pH 6.5 with a desensitizing, inward current. B, another NTS neuron shows an ASIC-like current to pH 6.5, but does not respond to pH 7.0. C, bar chart depicting the percentage of cells that respond to a stimulus of pH 6.5 or 7.0. While 100% of neurons respond to pH 6.5 (9/9), only 44.4% of neurons show an ASIC-like response to pH 7.0 (4/9).