Table 1.
Costs used in evaluation: 2009 prices
| Item | Cost (£) | Source |
|---|---|---|
| LBC test cost in laboratory* | 7.19 | Moss et al28 |
| HPV reflex test costs* | 12.83† | HPV Sentinel Sites Study |
| Consultation cost—general practitioner/nurse visit in community | 17.56 | Includes administration and smear taking time; based on 80% of smears taken by practice nurses25 |
| Outpatient visit | 71.34 | Martin-Hirsch et al29 |
| Colposcopy | 210 | Sherlaw-Johnson and Philips30 |
| Punch biopsy | 75.92 | Sherlaw-Johnson and Philips30 |
| Cone biopsy | 345.18 | Martin-Hirsch et al29 |
| Treatment‡: | ||
| CIN1 | 439.61 | Average cost per event29 |
| CIN2/3 | 617.97 | Average treatment cost of CIN2 and CIN3 from Martin-Hirsch et al29 |
| Cancer: | ||
| Stage I | 2785 | Average cost per event29 |
| Stage II | 4448 | |
| Stage III | 12 562 | |
| Stage IV | 12 777 |
CIN=cervical intraepithelial neoplasia; HPV=human papillomavirus; LBC=liquid based cytology.
*Including storage, transport, laboratory, sample media and vials; this cost is incurred only when cytology result is negative; when cytology result is borderline dyskaryosis or worse, management can be determined on basis of cytology alone.
†12.73 was used in cost effectiveness assessment for HPV used after treatment for CIN.
‡Averaged for proportion receiving loop electrosurgical excision procedure or cone by CIN grade.