Figure 2.

Absence of Both DAs in Respiratory Cilia and/or Spermatozoa Flagella of Individuals with LRRC6 Mutations

The electron micrographs of cross-sections of cilia and/or spermatozoa flagella from a control and individuals with identified LRRC6 mutations are shown. The blue flashes and triangles show the presence of ODAs and IDAs, respectively, and red flashes and triangles show their absence in affected individuals’ axonemes. Note the partial absence of DAs in the airway cilia of DCP193 (blue flash), whereas at the sperm level, the absence of DAs seems complete. Black scale bars represent 0.1 μm.