Table 7.
Circulating T-Cell Subset Levels in Controls, Patients With Chronic Stable Angina (CSA) and Acute Myocardial Infarction (AMI)
| Controls (n = 40) | CSA (n = 30) | AMI (n = 60) | |
|---|---|---|---|
| T-lymphocytes profile CD3+CD4+ | |||
| Naïve CD45RA+RO-CCR7+ | 29.3 (18.3–35.2) | 24.0 (17.9–33.8) | 24.4 (19.7–32.8) |
| Memory CD45RA-RO+ | 59.5 (15.9) | 65.0 (12.4) | 62.8 (12.6) |
| Central memory T | 49.3 (14.5) | 48.9 (10.9) | 46.6 (11.7) |
| Effector memory T | 9.2 (6.3–13.1) | 14.7 (9.2–22.2)* | 14.6 (10.0–17.9)† |
| CCR5+ | 9.1 (5.9–12.3) | 7.0 (5.2–17.4) | 9.3 (5.4–18.3) |
| CXCR3+ | 27.5 (22.1–33.0) | 28.9 (23.7–35.4) | 28.2 (21.3–31.5) |
| HLA-DR+ | 2.2 (1.3–4.0) | 5.8 (3.7–8.4)† | 5.9 (4.0–9.9)† |
*
<0.01
†
<0.001 vs controls.
Overall P=0.0001 for Effector Memory T (TEM), and overall P=0.002 for HLA-DR+ (Kruskal-Wallis test). Results are expressed as percentage of total CD3+CD4+T cells. Values are presented as mean (standard deviation) or as median (1° to 3° quartile) as appropriate.