Table 3.
Multivariable Analysis of Thrombolysis in Patients With Ischemic Stroke
| Characteristics | N | Number of Patients Receiving Thrombolysis (%) | OR (95% CI) | P |
|---|---|---|---|---|
| Sex | ||||
| Male | 564 | 53 (9.4) | 1.00 | 0.61 |
| Female | 518 | 66 (12.7) | 1.14 (0.68–1.92) | |
| Age, y | ||||
| <55 | 175 | 26 (14.9) | 1.00 | <0.001* |
| 55–64 | 171 | 19 (11.1) | 0.60 (0.26–1.37) | |
| 65–74 | 263 | 28 (10.7) | ||
| 75–84 | 311 | 33 (10.6) | 0.42 (0.20–0.89) | |
| ≥85 | 162 | 13 (8.0) | 0.29 (0.14–0.62) | |
| 0.17 (0.07–0.45) | ||||
| Ethnicity | ||||
| White | 731 | 85 (11.6) | 1.00 | 0.06 |
| Black | 252 | 23 (9.1) | 0.49 (0.26–0.95) | |
| Other | 77 | 10 (13.0) | 1.23 (0.50–3.06) | |
| Socioeconomic status | ||||
| Nonmanual | 179 | 14 (7.8) | 1.00 | 0.96 |
| Manual | 351 | 20 (5.7) | 0.94 (0.39–2.27) | |
| Economically inactive | 286 | 50 (17.5) | 0.79 (0.14–4.49) | |
| Prestroke living conditions | ||||
| Living alone | 351 | 32 (9.1) | 1.00 | 0.32 |
| Living with others Other | 608 | 74 (12.2) | 1.03 (0.59–1.80) | |
| 122 | 13 (10.7) | 0.54 (0.22–1.35) | ||
| Glasgow Coma Scale | ||||
| < 9 | 85 | 13 (15.3) | 1.00 | 0.12 |
| ≥ 9 | 966 | 105 (10.9) | 1.98 (0.82–4.83) | |
| Swallowing assessment | ||||
| Passed | 663 | 61 (9.2) | 1.00 | 0.61 |
| Failed | 262 | 51 (19.5) | 1.18 (0.63–2.21) | |
| NIHSS score in quartiles | ||||
| 1 (least severe) | 312 | 4 (1.3) | 1.00 | <0.001* |
| 2 | 296 | 21 (7.1) | 7.26 (2.05–25.73) | |
| 3 | 210 | 39 (18.6) | 23.23 (6.60–81.83) | |
| 4 (most severe) | 192 | 47 (24.5) | 53.72 (13.68–210.97) | |
| Time of day | ||||
| Daytime (6 am to 6 pm) | 623 | 88 (14.1) | 1.00 | <0.001 |
| Night (6 pm to 6 am) | 380 | 28 (7.4) | 0.37 (0.21–0.64) | |
| Day of the week | ||||
| Weekday | 777 | 92 (11.8) | 1.00 | 0.16 |
| Weekend | 305 | 27 (8.9) | 0.67 (0.38–1.18) | |
| Year of stroke | ||||
| Pre-FAST (2007/2008) | 326 | 55 (16.9) | 1.00 | 0.30 |
| Post-FAST (2009/2010) | 274 | 45 (16.4) | 1.33 (0.77–2.30) | |
OR indicates odds ratio.