Table 1.
Characteristics of Study Participants
| Matched Reference | ||
|---|---|---|
| Patients With CD | Individuals | |
| Total number of participants | 29 071 | 144 429 |
| Age, y | ||
| At study entry, median (range) | 30 (0–95) | 30 (0–95) |
| 0–19, n (%) | 11 799 (40.6) | 58 850 (40.7) |
| 20–39, n (%) | 5309 (18.3) | 26 376 (18.3) |
| 40–59, n (%) | 6469 (22.3) | 32 217 (22.3) |
| ≥60, n (%) | 5494 (18.9) | 26 986 (18.7) |
| Follow-up,* y | ||
| Median (range) | 9.1 (0–39.6) | 9.0 (0–39.5) |
| Mean±SD | 10.4±6.4 | 10.3±6.4 |
| Sex, n (%) | ||
| Female | 18 001 (61.9) | 89 526 (61.9) |
| Male | 11 070 (38.1) | 54 903 (38.1) |
| Calendar year, n (%) | ||
| Before or during 1989 | 4105 (14.1) | 20 375 (14.1) |
| 1990–1999 | 12 054 (41.5) | 59 841 (41.4) |
| During or after 2000 | 12 912 (44.4) | 64 213 (44.5) |
| Entry year, median (range) | 1998 (1969–2008) | 1998 (1969–2008) |
| Type 1 diabetes,† n (%) | 922 (3.2) | 536 (0.4) |
| Autoimmune thyroid disease, n (%) | 204 (0.7) | 324 (0.2) |
| Age at DCM diagnosis, y, median (range) | 58 (17–82) | 64 (2–87) |
| Age from study entry to DCM diagnosis, y, median (range) | 6 (0–23) | 7 (0–27) |
*
Follow-up until diagnosis of DCM, death, emigration, or December 31, 2008. In reference individuals follow-up can also end through small-intestinal biopsy.
†
Type 1 diabetes was defined according to age at first diagnosis with diabetes mellitus (<30 y).