Table 3.
Healthy Subjects (n=10) | Patients With NYHA Class II Heart Failure` (n=10) | Patients With NYHA Class IV Heart Failure (n=10) | |
---|---|---|---|
Sex, male/female | 7/3 | 8/2 | 7/3 |
Age, y | 56.4±9.9 (38–74) | 69.7±9.3* | 72.8±10.8 (53–88)* |
Height, cm | 170.1±8.2 (158–187) | 171.1±10.0 (157–191) | 169.5±4.8 (163–178) |
Weight, kg | 79.6±15.6 (54–113) | 79.0±16.7 (57–104) | 79.1±7.7 (70–92) |
Resting measurements | |||
LVEF, % | … | 26.7±6.7 (17–39) | 20.8±6.6 (13–37) |
SV, mL | … | 64.5±13.2 (42–81) | 62.5±15.3 (34–81) |
Q, L/min | … | 4.2±0.9 (3.0–5.5) | 4.3±1.1 (2.2–6.6) |
CI, L/min per square meter | … | 2.2±0.5 (1.6–3.2) | 2.2±0.6 (1.1–3.1) |
HR, bpm | 62.3±5.2 (52–71) | 65.2±7.1 (55–77) | 69.8±7.8 (59–85) |
SBP, mm Hg | 126.8±11.2 (109–138) | 116±24.9 (90–160) | 127.4±202.2 (100–170) |
DBP, mm Hg | 71.2±9.1 (63–87) | 66.8±10.7 (50–82) | 74.1±14.9 (50–100) |
Data are shown as mean±SD and range (minimum–maximum).
LVEF indicates left ventricular ejection fraction; SV, stroke volume; Q, cardiac output; CI, cardiac output index; HR, heart rate; SBP, systolic blood pressure; and DBP, diastolic blood pressure.
P<0.01, analysis of variance, repeated comparison with healthy subjects. No significant differences between NYHA Classes II and IV.