. 2012 Jun 22;1(3):e001883. doi: 10.1161/JAHA.112.001883

Table 4.

Key Measurements of Cardiopulmonary Exercise Testing in Healthy Subjects and Patients With Heart Failure of Different Severities

	Healthy Subjects (n=10)	Patients With NYHA Class II Heart Failure (n=10)`	Patients With NYHA Class IV Heart Failure (n=10)
Peak

L/min	1.96±0.56 (1.3−3.1)	1.01±0.31 (0.49−1.45)^***	0.62±0.21 (0.36−1.12)^****^††

mL/min per kilogram	24.8±6.0 (17.4−37.3)	13.2±4.6 (4.9−22.6)^***	7.8±2.5 (4.4−13.4)^**** ^††

% Predicted	95.8±8.6 (81−107)	59.0±20.8 (36−105)^***	40.3±15.7 (21−68)^**** ^†

AT

L/min	1.11±0.29 (0.71−1.51)	0.74±0.14 (0.50−1.00)^**	0.50±0.13 (0.40−0.82)^***^††

mL/min per kilogram	14.0±3.3 (10.5−20.6)	9.9±2.8 (7.5−17.3)^*	6.3±1.6 (4.7−9.8)^**** ^††

% Predicted	98.5±12.8 (79−123)	64.7±23.7 (44−130)^**	44.4±7.4 (34−56)^**** ^†

Peak O₂P

mL/beat	12.7±3.3 (8.1−18.7)	9.7±4.1 (4.6−16.4)	6.4±1.7 (2.8−8.8)^*** ^†

% Predicted	95.8±8.6 (81−107)	82.4±26.5 (46−123)	61.4±19.2 (24−93)^*** ^†

vs

Slope	25.8±3.8 (22−33)	38.8±9.3 (27−55)^**	49.2±11.2 (34−75)^**** ^†

% Predicted	106.9±14.8 (89−131)	141.7±25.6 (105−190)^*	163.3±44.8 (106−261)^**

Highest

mL/L	40.8±5.2 (30–47)	28.7±5.3 (21–36)^***	20.7±1.6 (18–24)^**** ^†††

% Predicted	100.3±11.3 (71–114)	83.2±15.4 (58–96)^**	57.8±4.7 (49–66)^**** ^†††

at highest , L/min	1.07±0.30 (0.69–1.49)	0.59±0.18 (0.35–0.95)^**	0.42±0.10 (0.25–0.62)^**** ^††

at highest , L/min	26.9±6.2 (19–40)	23.9±6.7 (13–35)	21.8±6.1 (13–33)

Highest

mL/L	34.6±5.6 (26.2–41.8)	25.3±4.7 (18–35)^**	19.0±1.6 (17–22)^**** ^††

% Predicted	101.4±12.1 (81–117)	73.7±12.2 (53–95)^***	56.5±5.3 (47–66)^**** ^††

at highest , L/min	0.96±0.17 (0.68–1.21)	0.69±0.15 (0.44–0.94)^*	0.47±0.12 (0.39–0.78)^**** ^††

at highest , L/min	28.9±6.2 (22–42)	26.7±5.8 (15–35)	23.9±6.4 (17–38)

Data are shown as mean±SD and range (minimum–maximum).

Peak Inline graphic indicates oxygen uptake at maximum exercise; AT, oxygen uptake at anaerobic threshold; O₂P, oxygen pulse; vs , slope of against ; highest , 90-s averaged highest value of ratio of ; and highest , 90-s averaged highest value of ratio of .