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. 2012 Jun 22;1(3):e001644. doi: 10.1161/JAHA.112.001644

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© 2012 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 2. — Left, Ischemic risk zone (fraction LV) and infarct size (fraction risk zone) in rabbits with risk zones >20% of the LV exposed to in vivo ischemia/reperfusion (30 min/3 h) in combined Bendavia treatment group and vehicle group (mean±SEM; P=0.09, t test). Note similarity to data observed in the sheep model (text, Figure 1). Right, Relationship between the extent of the ischemic risk zone (g) and the extent of necrosis (g) in combined Bendavia group and vehicle group. Regression lines: vehicle is indicated by dashed line; Bendavia, solid line.