Table 2.
Discontinuation of Study Drugs According to the Randomized Groups
| Aspirin (n = 502) | Clopidogrel (n = 499) | P* | |
|---|---|---|---|
| Discontinuation† of study drug | 32 | 63 | 0.001 |
| Change to dual-antiplatelet treatment‡ | 23 | 23 | 0.98 |
| Change to warfarin | 5 | 10 | 0.19 |
| Dyspepsia, peptic ulcer | 3 | 5 | 0.47 |
| Diarrhea | 0 | 4 | 0.04 |
| Rash | 0 | 5 | 0.03 |
| Other | 1 | 16¶ | <0.001 |
Values are given as numbers of patients.
P for differences between groups.
Discontinuation defined as being off the randomized principle for >28 days.
Patients undergoing new percutaneous coronary intervention with stent implantation without reaching an end point.
Includes dizziness (n=3), general discomfort (n=3), and discontinuation due to change of medication beyond the study protocol.