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. 2012 Jun 22;1(3):e000703. doi: 10.1161/JAHA.112.000703

Table 3.

Baseline Characteristics of the Aspirin Group (n=502) According to the Presence of High or Low RPR

High RPR (n=128) Low RPR (n=374) P*
Age, y, mean (range) 61.9 (44.9–80.3) 62.1 (36.4–80.8) 0.85

Sex, female, n (%) 31 (24.2) 81 (21.7) 0.55

Race, white, n (%) 119 (93.0) 364 (97.3) 0.07

Cardiovascular risk factors, n (%)

 Current smoking 31 (24.2) 77 (20.6) 0.39

 History of hypertension 63 (49.2) 209 (55.9) 0.19

 Diabetes mellitus 29 (22.7) 76 (20.3) 0.58

 Previous myocardial infarction 60 (46.9) 149 (39.8) 0.16

 Intermittent claudication 5 (3.9) 24 (6.4) 0.29

 Previous percutaneous coronary intervention 96 (75.0) 281 (75.1) 0.98

 Previous coronary artery bypass grafting 26 (20.3) 77 (20.6) 0.95

Body mass index, kg/m2, median (25th, 75th percentiles) 26.9 (25.4, 29.3) 27.4 (24.9, 30.3) 0.52

Total cholesterol, mmol/L, mean±SD 4.46±0.89 4.60±0.99 0.14

High-density lipoprotein cholesterol, mmol/L, mean±SD 1.31±0.37 1.34±0.45 0.55

Low-density lipoprotein cholesterol, mmol/L, mean±SD 2.45±0.76 2.57±0.86 0.18

Triglycerides, mmol/L, median (25th, 75th percentiles) 1.32 (0.95, 1.90) 1.39 (0.93, 1.89) 0.61

Platelet count, ×109/L, median (25th, 75th percentiles) 231 (203, 273) 224 (193, 264) 0.05

Mean platelet volume, fL, mean±SD 10.99±0.85 10.87±0.94 0.21

C-reactive protein, mg/L, median (25th, 75th percentiles) 1.85 (1.1, 3.4) 1.90 (0.9, 3.4) 0.33

vWF, %, median (25th, 75th percentiles) 125 (98, 145) 100(79, 125) <0.001

TxB2, ng/mL, mean (range) 2.9 (0.0–15.0) 2.6 (0.0–21.0) 0.32

Medication, n (%)

 Statins 128 (100) 367 (98.1) 0.15

 β-Blockers 99 (77.3) 284 (75.9) 0.86

 Calcium channel blockers 26 (20.3) 97 (25.9) 0.21

 Angiotensin-converting enzyme inhibitors 31 (24.2) 90 (24.1) 0.93

 Angiotensin receptor blockers 30 (23.4) 100 (26.7) 0.48

 Proton pump inhibitors 13 (10.2) 44 (11.8) 0.62

Values are given as n (%), mean±SD, mean (range), median (25th, 75th percentiles), or percentage, as indicated.

*

P for differences between groups.

Definitions as given in Table 1.