Table 3.
Baseline Characteristics of the Aspirin Group (n=502) According to the Presence of High or Low RPR
| High RPR (n=128) | Low RPR (n=374) | P* | |
|---|---|---|---|
| Age, y, mean (range) | 61.9 (44.9–80.3) | 62.1 (36.4–80.8) | 0.85 |
| Sex, female, n (%) | 31 (24.2) | 81 (21.7) | 0.55 |
| Race, white, n (%) | 119 (93.0) | 364 (97.3) | 0.07 |
| Cardiovascular risk factors, n (%) | |||
| Current smoking | 31 (24.2) | 77 (20.6) | 0.39 |
| History of hypertension | 63 (49.2) | 209 (55.9) | 0.19 |
| Diabetes mellitus | 29 (22.7) | 76 (20.3) | 0.58 |
| Previous myocardial infarction | 60 (46.9) | 149 (39.8) | 0.16 |
| Intermittent claudication | 5 (3.9) | 24 (6.4) | 0.29 |
| Previous percutaneous coronary intervention | 96 (75.0) | 281 (75.1) | 0.98 |
| Previous coronary artery bypass grafting | 26 (20.3) | 77 (20.6) | 0.95 |
| Body mass index, kg/m2, median (25th, 75th percentiles) | 26.9 (25.4, 29.3) | 27.4 (24.9, 30.3) | 0.52 |
| Total cholesterol, mmol/L, mean±SD | 4.46±0.89 | 4.60±0.99 | 0.14 |
| High-density lipoprotein cholesterol, mmol/L, mean±SD | 1.31±0.37 | 1.34±0.45 | 0.55 |
| Low-density lipoprotein cholesterol, mmol/L, mean±SD | 2.45±0.76 | 2.57±0.86 | 0.18 |
| Triglycerides, mmol/L, median (25th, 75th percentiles) | 1.32 (0.95, 1.90) | 1.39 (0.93, 1.89) | 0.61 |
| Platelet count, ×109/L, median (25th, 75th percentiles) | 231 (203, 273) | 224 (193, 264) | 0.05 |
| Mean platelet volume, fL, mean±SD | 10.99±0.85 | 10.87±0.94 | 0.21 |
| C-reactive protein, mg/L, median (25th, 75th percentiles) | 1.85 (1.1, 3.4) | 1.90 (0.9, 3.4) | 0.33 |
| vWF, %, median (25th, 75th percentiles) | 125 (98, 145) | 100(79, 125) | <0.001 |
| TxB2, ng/mL, mean (range) | 2.9 (0.0–15.0) | 2.6 (0.0–21.0) | 0.32 |
| Medication, n (%) | |||
| Statins | 128 (100) | 367 (98.1) | 0.15 |
| β-Blockers | 99 (77.3) | 284 (75.9) | 0.86 |
| Calcium channel blockers | 26 (20.3) | 97 (25.9) | 0.21 |
| Angiotensin-converting enzyme inhibitors | 31 (24.2) | 90 (24.1) | 0.93 |
| Angiotensin receptor blockers | 30 (23.4) | 100 (26.7) | 0.48 |
| Proton pump inhibitors | 13 (10.2) | 44 (11.8) | 0.62 |
Values are given as n (%), mean±SD, mean (range), median (25th, 75th percentiles), or percentage, as indicated.
P for differences between groups.
Definitions as given in Table 1.