Table 4.
Clinical Endpoints Among Aspirin Users (n=502) According to High or Low RPR as Determined by PFA100 and Among Patients With High On-Aspirin RPR (n=259) According to the Randomized Groups
| Aspirin Users (n=502) | Patients With High On-Aspirin RPR (n=259) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Endpoints | No. | High RPR (n=128) | Low RPR (n=374) | Rate Ratio (95% CI) | P | No. | Aspirin (n=128) | Clopidogrel (n=131) | Rate Ratio (95% CI) | P |
| Composite | 54 | 17 (13.3) | 37 (9.9) | 1.34 (0.76, 2.38) | 0.31 | 27 | 17 (13.3) | 10 (7.6) | 1.74 (0.80–6.77) | 0.16 |
| Unstable angina | 15 | 4 (3.1) | 11 (1.9) | 1.06 (0.34, 3.34) | 0.92 | 8 | 4 (3.1) | 4 (3.1) | 1.02 (0.26–4.09) | 0.97 |
| Myocardial infarction | 18 | 8 (6.3) | 10 (2.7) | 2.34 (0.92, 5.92) | 0.07 | 12 | 8 (6.3) | 4 (3.1) | 2.05 (0.62–6.80) | 0.23 |
| Ischemic stroke | 17 | 4 (3.1) | 13 (3.5) | 0.90 (0.29, 2.76) | 0.85 | 6 | 4 (3.1) | 2 (1.5) | 2.05 (0.37–11.17) | 0.39 |
| Death | 4 | 1 (0.8) | 3 (0.8) | 0.97 (0.10, 9.36) | 0.98 | 1 | 1 (0.8) | 0 (0.0) | Undefined | 0.31 |
| Person-years | … | 256 | 748 | … | … | … | 256 | 262 | … | … |
Values are given as No. patients (%).