Table 5.

Estimated Effects on CMR Parameters Associated With a 20% Increase in IMR (mm Hg/s) Derived From Multivariable Models With Adjustment for Confounders at Both Time Points

	IMR Effect	95% CI	P
Multivariable associations,* early CMR (2 days)
Area at risk, %	0.98	0.33 to 1.64	0.004
Infarct size, %	1.68	1.01 to 2.34	<0.001
Myocardial salvage index, %	−3.43	−4.86 to −2.00	<0.001
Microvascular obstruction, %	0.21	0.02 to 0.40	0.028
Hemorrhage, %	0.19	0.08 to 0.31	0.002
Left ventricular ejection fraction, %	−0.64	−1.16 to −0.12	0.017
Multivariable associations,† late CMR (3 months)
Infarct size, %	−0.08	−0.47 to 0.31	0.680
Myocardial salvage index, %	−0.19	−1.31 to 0.94	0.744
Left ventricular ejection fraction, %	−0.19	−0.56 to 0.18	0.315

Results are additive effects on the CMR parameter.

^*For all baseline CMR outcomes, adjustment was made for the following variables: previous MI, sex, pain‐to‐balloon time, door‐to‐balloon time, thrombectomy, catheterization laboratory pulse pressure, TIMI flow, corrected TIMI frame count, and percent of ST elevation still present after PCI.

^†For all follow‐up CMR outcomes, we adjusted for baseline value of the CMR parameter, age, door‐to‐balloon time, glycoprotein IIb/IIIa, TIMI flow, and percent of ST elevation still present after PCI.