Table 3.

Systemic and LV Hemodynamics in CAMK4^+/+ and CAMK4^−/− Mice 8 Weeks After Myocardial Infarction

	CaMK4+/+ (n=12)	CaMK4−/− (n=14)
HR, bpm	498±20	482±18
SBP, mm Hg	100±0.5	108±0.6*
DBP, mm Hg	74±0.3	82±0.4*
LVEDD, mm	4.16±0.12	4.6±0.11*
LVESD, mm	3.15±0.08	3.71±0.13*
IVS, mm	0.66±0.04	0.85±0.05*
LVPW, mm	0.68±0.03	0.86±0.03*
LVFS, %	24.74±2.9	17.8±2.3*
LVEF, %	49.02±4.8	35.8±3.4*
+dP/dt, mm Hg/s	3784±402	3004±382*
−dP/dt, mm Hg/s	3918±386	3128±394*

Data are mean±SE. Mice were 8 months old (myocardial infarction was induced in 6-month-old animals). HR indicates heart rate; SBP, systolic BP; DBP, diastolic BP; LVEDD, LV end-diastolic diameter; LVESD, LV end-systolic diameter; IVS, interventricular septum; LVPW, LV posterior wall; LVFS, LV fractional shortening; and LVEF, LV ejection fraction.

^*P<0.05; otherwise, P not significant.