Table 1.
Baseline Characteristics of Individuals Classified as Low Risk by FRS According to Cardiorespiratory Fitness Quintile (n=11 190)
| Fitness Quintiles | ||||||
|---|---|---|---|---|---|---|
| Q1 (n=2072) | Q2 (n=2191) | Q3 (n=2369) | Q4 (n=2294) | Q5 (n=2264) | P | |
| Age, y, mean±SD | 40.6±4.2 | 41.1±4.4 | 40.5±4.3 | 40.7±4.3 | 40.6±4.4 | 0.02 |
| Follow-up time, y, mean±SD | 27.5±5.2 | 27.2±4.6 | 27.4±4.1 | 26.9±4.3 | 26.5±3.9 | <0.001 |
| FRS: | <0.001 | |||||
| mean±SD | 5±2 | 5±2 | 5±2 | 4±2 | 4±2 | |
| n (%) | ||||||
| <6% | 1197 (58) | 1365 (62) | 1603 (68) | 1662 (72) | 1854 (82) | |
| 6% to 9% | 875 (42) | 826 (38) | 766 (32) | 632 (28) | 410 (18) | |
| Cardiorespiratory fitness, METs, mean (95% CI) | <0.001 | |||||
| Men | 8.7 (4.4–9.9) | 10.2 (9.4–10.8) | 11.4 (10.3–12.2) | 12.6 (11.3–13.5) | 14.8 (12.6–22.5) | |
| Women | 6.6 (4.4–7.6) | 7.7 (6.3–8.5) | 8.7 (8.1–9.4) | 9.5 (8.5–10.3) | 11.5 (9.9–18.3) | |
| BMI, kg/m2, mean±SD | <0.001 | |||||
| Men | 27.9±4.3 | 26.3±2.9 | 25.4±2.5 | 24.9±2.3 | 23.9±2.0 | |
| Women | 24.4±5.1 | 22.5±3.2 | 21.9±2.8 | 21.3±2.2 | 20.6±1.6 | |
| Physical activity, n (%) | <0.001 | |||||
| No organized physical activity | 1520 (73) | 1264 (58) | 1057 (45) | 611 (26) | 349 (15) | |
| Nonrunning activities | 309 (15) | 444 (20) | 466 (20) | 373 (16) | 231 (10) | |
| Running 0 to 10 miles/week | 221 (11) | 430 (20) | 737 (31) | 979 (43) | 749 (33) | |
| Running 11 to 20 miles/week | 16 (0.7) | 49 (2) | 92 (4) | 265 (12) | 497 (22) | |
| Running >20 miles/week | 6 (0.3) | 4 (0.2) | 17 (0.7) | 67 (3) | 438 (20) | |
| Total cholesterol, mg/dL, mean±SD | 205.5±33.8 | 205.1±34.4 | 202.9±33.3 | 200.0±32.9 | 195.5±30.0 | <0.001 |
| Systolic blood pressure, mm Hg, mean±SD | 119.0±13.0 | 116.5±12.5 | 116.2±12.2 | 115.2±12.5 | 115.4±12.6 | <0.001 |
| Diastolic blood pressure, mm Hg, mean±SD | 79.9±9.0 | 78.6±8.7 | 77.8±8.3) | 76.9±8.6 | 76.5±8.2 | <0.001 |
| Fasting glucose, mg/dL, mean±SD | 98.9±17.3 | 97.6±13.6 | 96.5±10.5 | 95.6±10.0 | 95.5±9.8 | <0.001 |
| Family history of premature CHD, n (%) | 29 (1.4) | 14 (0.6) | 10 (0.4) | 7 (0.3) | 10 (0.4) | <0.001 |
| Smoker, n (%) | 499 (24) | 424 (19) | 363 (15) | 272 (12) | 165 (7) | <0.001 |
Values are given as mean ± standard deviation or number (percentage) of patients, as noted.
*Running, jogging, or walking activities.