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Gαs protein knockdown in the sinoatrial node. Expression of Gαs protein was assessed by immunohistochemistry. (A) Representative microscopic findings after treatment with Ad-siRNA-Gαs and Ad-GFP (scale bar, 50 μm). (B) Quantification of Gαs protein levels in n=5 animals per group. Data are expressed as mean±SEM (***P<0.001 vs Ad-GFP). GFP indicates green fluorescent protein.
