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. Author manuscript; available in PMC: 2013 Oct 23.
Published in final edited form as: ACS Nano. 2012 Sep 24;6(10):8783–8795. doi: 10.1021/nn303833p

Figure 3.

Figure 3

Imaging of metastases. (a) Micromorphological imaging of normal and tumor vasculature at 99 Jm resolution of a metastatic 4T1 tumor (week 5) using a Siemens Inveon micro-CT and a liposome-based iodinated contrast agent. (b) Co-registration of the micro-CT image with the FMT image of the same animal injected with the RGD-NC nanoparticles. (c) The ROIs indicate the location of the tumor and different organs as obtained from previously published work.41 (d) Using a CRi Maestro fluorescence imaging system, ex vivo imaging of organs indicates the colocalization of RGD-NC particles and 4T1 metastatic cells expressing GFP.