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. 2012 Nov;97(11):1743–1750. doi: 10.3324/haematol.2011.059584

Figure 1.

Figure 1.

Flow chart of the study design. Relapses occurred in 43 and 119 ETV6/RUNX1-positive and –negative cases of ALL, respectively. Testicular relapses were more frequent in ETV6/RUNX1-positive ALL (P=0.04) without any increase in other extramedullary sites of disease. Second complete remission was achieved in 98% of ETV6/RUNX1-positive ALL and in 82% of ETV6/RUNX1-negative ALL. CRI: first complete remission; BM: bone marrow; CNS: central nervous system.