Figure 11.

Transformation of band-pass rMTF to low-pass rMTF by reducing GABA_A. IC Adapting model with 3 user-defined low-pass excitatory inputs (LSO sync tuning) and 3 VNLL band-pass inhibitory inputs (rBMF = 12 Hz). (A) Example voltage traces from individual trials at 16 Hz modulation frequency for a young (left) and aged (right) model neuron. (B) A band-pass rMTF (solid blue) from a model young neuron is transformed into a low-pass rMTF (dashed, blue) upon 50% reduction in GABA_A. The original vector strength (solid red) decreased (dashed, red) but the cut-off frequency remained the same. Firing rate, in spikes/s, and vector strength are marked along opposing Y-axes and modulation frequency is marked along the X-axis in Hz.