Table 3. Comparison of 13C MFA flux measurements [35] vs. model-predicted flux ranges.
| Reaction | Flux measurements by Young et al., 2011 [35] | Flux ranges predicted by iJN678 model (With max biomass) | Flux ranges predicted by iSyn731 model (With max biomass) | |||
| 95% LB | 95% UB | LB | UB | LB | UB | |
| RBC | 123.00 | 132.00 | 109.02 | 109.10 | 102.49 | 106.33 |
| PGK | 219.00 | 237.00 | 187.11 | 187.25 | 182.70 | 182.92 |
| 13PDG | 219.00 | 237.00 | 187.11 | 196.36 | 182.70 | 201.96 |
| GAPDH | 90.00 | 99.00 | 74.98 | 75.07 | 73.40 | 73.50 |
| FBA | 53.00 | 66.00 | −0.17 | 74.85 | −0.08 | 73.17 |
| FBP | 53.00 | 66.00 | 0.00 | 74.85 | 0.00 | 73.17 |
| PGI | 15.00 | 24.00 | 0.68 | 0.73 | 0.82 | 0.84 |
| G6PD | 12.00 | 21.00 | 0.00 | 0.05 | 0.00 | 0.03 |
| 6PGL | 12.00 | 21.00 | 0.00 | 0.05 | 0.00 | 0.03 |
| 6PGD | 12.00 | 21.00 | 0.00 | 0.05 | 0.00 | 0.03 |
| PRK | 123.00 | 132.00 | 109.02 | 109.10 | 106.24 | 106.32 |
| SBGPL | 29.00 | 43.00 | −0.17 | 74.85 | −0.08 | 73.17 |
| SBP | 29.00 | 43.00 | 0.00 | 74.85 | 0.00 | 73.17 |
| TAL | −6.00 | 9.00 | −36.74 | 38.28 | −35.93 | 37.32 |
| TKT1 | 37.20 | 37.50 | 36.57 | 36.60 | 36.66 | 36.79 |
| RPI | 35.40 | 35.70 | 35.18 | 35.21 | 35.82 | 35.86 |
| TKT2 | 35.40 | 35.70 | 37.25 | 37.28 | 36.18 | 36.23 |
| RPE | 75.50 | 76.20 | 73.83 | 73.88 | 72.01 | 72.10 |
| PGM | 22.90 | 23.60 | 26.83 | 26.95 | 25.92 | 29.79 |
| ENO | 23.40 | 23.80 | 26.84 | 26.95 | 25.92 | 29.79 |
| PYK | 7.90 | 11.10 | 0.00 | 13.88 | 0.00 | 16.72 |
| PDH | 11.50 | 12.00 | 0.00 | 8.97 | 0.00 | 13.46 |
| CS | 3.00 | 3.40 | 2.15 | 2.21 | 1.35 | 1.37 |
| ACONT | 3.00 | 3.40 | 2.15 | 2.21 | 1.35 | 1.37 |
| ICD | 3.00 | 3.00 | 2.15 | 2.21 | 1.32 | 1.37 |
| SUCD | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 |
| FUM | 1.70 | 2.00 | −5.44 | 1.55 | −7.26 | 1.49 |
| MDH | 1.90 | 5.20 | 5.35 | 5.61 | 7.15 | 7.32 |
| ME1 | 3.70 | 6.90 | 0.00 | 0.17 | 0.00 | 0.08 |
| ME2 | 3.70 | 6.90 | − | − | 0.00 | 0.08 |
| PPC | 9.90 | 13.20 | 11.74 | 11.98 | 12.25 | 12.37 |