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In vitro effects of VIP treatment on ECM mRNA expression levels from B6- and BALB/c-derived fibroblasts. Fibroblasts were stimulated with LPS (25 μg/mL) + VIP treatment (10−9 M) for 18 hours. The relative mRNA levels of ITG-α1 (A), CD44 (B), LAMA-1 (C), ECM1 (D), VCAN (E), and SPP1 (F) were determined by real-time RT-PCR. *P < 0.001.
