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Extra-renal causes that affect creatinine and BUN levels.
| Creatinine | BUN | ||
| Elevated | Low | Elevated | Low |
| ↑Muscle Mass | ↓Muscle Mass | Hypercatabolism | Liver Disease |
| Muscle Injury (rhabdornyolysis) | Volume Depletion | Starvation | |
| Drugs: Cefoxitin | Steroids | ||
| Cimetidine | CHF | ||
| TMP-SMZ | Hydroxyurea | ||
| Supplements: Creatine | Tissue Necrosis (gangrene) | ||
| Intraperitoneal Urine | |||
| Extravasation | |||
