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. Author manuscript; available in PMC: 2013 Oct 30.
Published in final edited form as: Brain Res. 2012 Sep 11;1482:47–54. doi: 10.1016/j.brainres.2012.09.005

Figure 8.

Figure 8

Correlation analysis between CART density and cocaine-induced LMA in rats at 23 weeks after intra-NAc injections. The data represents individual values for all rats in both the shRNA and scrambled RNA groups. Each animal had a total of 2 microinjections (bilateral), one into each hemisphere and therefore 2 measurements corresponding to each brain were taken/rat for the CART density in the NAc (see Figure 7 legend). The difference between cocaine and saline total LMA (cocaine LMA 30 min – saline LMA 30 min) for each rat was plotted on the x-axis and the CART peptide density for the rat was plotted on the y-axis. The difference between cocaine and saline LMA represents the actual cocaine effect. The analysis shows that there is a correlation between CART density and cocaine-saline LMA (r = −0.5992, R2 = 0.3591, *p = 0.0395).