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In vitro targeting and inhibition of laminin chain synthesis by Polycefin. Immunofluorescent confocal microscopy of U87MG glioma cultures stained for laminin chains. Left, untreated control cells expressing α4 and β1 laminin-8 chains. Right, Polycefin that bears AONs to α4 and β1 chains markedly inhibits the expression of both laminin chains. Nuclei are counterstained with DAPI
