Table 3.
Overall and group stratified effect of independent intervention hours on follow-up child outcomes, adjusting for baseline age, modified Autism Diagnostic Observation Schedule social affect and baseline child outcomes, n=98.
| Overall | P-ESDM Group | Community Group | Interaction p value | |
|---|---|---|---|---|
| Coefficient (95% CI) | Coefficient (95% CI) | Coefficient (95% CI) | ||
| Modified ADOS Social Affect | −0.46(−0.99,0.07) | 0.65(−0.46,1.76) | −0.56(−1.22,0.11) | 0.166 |
| ADOS Restrictive and Repetitive | −0.11(−0.22,0)* | −0.1(−0.34,0.14) | −0.08(−0.22,0.06) | 0.737 |
| Mullen DQ | 0.78(0.08,1.47) * | 1.52(−0.05,3.09) | 0.63(−0.25,1.51) | 0.289 |
| Mullen Verbal IQ | 1.09(0.11,2.06) * | 2.15(−0.04,4.33) | 0.81(−0.4,2.03) | 0.258 |
| Mullen Nonverbal IQ | 0.43(−0.27,1.13) | 0.75(−0.75,2.25) | 0.36(−0.57,1.3) | 0.644 |
| MCDI words and Gestures part I: Phrases understood | 0.13(−0.3,0.55) | −0.14(−1.19,0.92) | 0.07(−0.42,0.57) | 0.702 |
| MCDI words and Gestures part I: Vocabulary Comprehension | 4.22(0.15,8.3) * | 9.99(1.34,18.65) * | 1.31(−4.09,6.72) | 0.06 |
| MCDI words and Gestures part I: Vocabulary Production | 1.31(−1.45,4.07) | 9.36(3.74,14.97) * | −0.96(−4.47,2.54) | 0.005 |
| MCDI words and Gestures part II: Total Gestures | 0.33(−0.29,0.94) | 0.53(−0.92,1.98) | 0.14(−0.65,0.93) | 0.507 |
| Imitative Sequences Score | 0.17(−0.03,0.37) | 0.02(−0.47,0.52) | 0.23(−0.01,0.46) | 0.469 |
| Social Orient Average Score | 0(−0.02,0.01) | −0.02(−0.06,0.02) | 0(−0.03,0.02) | 0.616 |
| Nonsocial Orient Average Score | −0.02(−0.04,0) * | −0.03(−0.07,0.01) | −0.02(−0.03,0) | 0.403 |
| Joint Orient: Average Score | 0(−0.02,0.02) | 0.01(−0.03,0.05) | −0.01(−0.03,0.02) | 0.494 |
Note: ADOS = Autism Diagnostic Observation Scale for Toddlers; DQ = Developmental Quotient; MCDI = MacArthur-Bates Communicative Development Inventory; P-ESDM = Parent Delivery–Early Start Denver Model.
*
p value ≤ 0.05